Logan Health Center clinical faculty demonstrate value of diagnostic ultrasound for muscular dystrophy patients

August 16, 2019 -- A recent case study authored by members of the department of radiology and a Health Center clinician was published in Journal of Ultrasound. It reported that an 8-year-old patient with Duchenne muscular dystrophy (DMD) displayed increased sonoelastographic measures (hardening) of lower extremity muscles when compared with an age-matched healthy control. The report also demonstrated the value of using sonoelastography, a noninvasive ultrasound technique, to diagnose and monitor the progress of DMD.

The case study, titled “Sonoelastography of the trunk and lower extremity muscles in a case of Duchenne muscular dystrophy,” was written by Stacey Cornelson, DC, DACBR; Ashley Ruff, DC; Muriel Perillat, DC, MS,; and Norman Kettner, DC, DACBR, FICC, professor and chair of the Department of Radiology.

DMD is a rare genetic disorder that causes muscle weakness and reduced tone of the core and lower extremities through replacement of muscle by fibrofatty tissue. Sonoelastography ultrasound can be used to demonstrate changes in the muscle mechanical properties due to fatty replacement and fibrosis. Thus far, the use of ultrasound technology in diagnosing DMD patients has been limited. Muscle biopsy is the standard for histologic diagnosis of DMD, but ultrasound may be a noninvasive and more cost-effective approach to assess muscle changes and response to treatment. A goal of this case report was to add to the growing argument for this approach.

The case study also demonstrated the value of chiropractic care for treating DMD symptoms. The patient came to Dr. Perillat for palliative care of low back and bilateral leg pain and headaches. Among other symptoms, a physical exam revealed a mild waddling gait, bilateral pseudohypertrophy of the calf muscles and abnormal spinal ranges of motion. The patient also required assistance to climb a flight of stairs.

In addition to sonoelastographic ultrasound to assess muscle stiffness and texture, the patient underwent spinal mobilization, kinesiotaping of lower extremity muscles and was also fitted for foot orthotics to ease the abnormal gait. The patient reported pain reduction and some improvement in gait and required less assistance to climb stairs. 

Stanford Instructor Discusses MRI in Chiropractic at Logan

August 9, 2019 -- Kenneth Weber II, DC, PhD, an instructor in the Department of Anesthesiology, Perioperative and Pain Medicine at Stanford University, recently spoke as part of the Logan Department of Radiology’s Chiropractic Grand Rounds.

Dr. Weber, who earned his clinical training as a chiropractor at Palmer College of Chiropractic Florida and then completed a PhD in neuroscience at Northwestern University, currently researches different neuroscience, machine-learning and clinical research techniques to better understand, treat, and prevent musculoskeletal and neurological conditions, including spinal pain.

On August 2, he addressed the topic of advancing chiropractic with advanced magnetic resonance imaging to students, faculty and staff, opening with a general description of the structural and functional magnetic resonance imaging (fMRI) technology along with their advantages and disadvantages. He described how fMRI provides non-invasive mapping of the brain’s neuroanatomy and neurophysiology in the assessment of patients with chronic pain. Maladaptive neural circuity develops as an adaptive response to the persistent nociception. This adaptation to central sensitization utilizes cortical and subcortical neuroplasticity, and these patterns of brain neural activity are mapped with fMRI technology. Dr. Weber discussed his research in brain-based models of clinical pain states, and has incorporated an artificial intelligence method known as machine learning to enhance models of bran responses to pain. 

He also explained his extensive research of spinal manipulation in healthy and clinical pain disorders, including a new development in his research: spinal cord fMRI. This technique, which Dr. Kettner said has been long hampered by technical challenges, is advancing and may provide a biomarker of spinal cord injury and disorders. In addition, simultaneous fMRI of the spinal cord combined with functional imaging of the brain is now on the horizon.

Dr. Kettner said this corticospinal mapping will provide a perspective of large neural network integration, allowing more precise understanding of chronic pain and other associated disorders, such as anxiety and depression, and their treatment outcomes.  


Dr. Stacey Cornelson Earns DACBR Status

July 29, 2019 -- Please join us in congratulating Stacey Cornelson, DC who recently earned the Diplomate (DACBR) status by the American Chiropractic Board of Radiology.

Dr. Cornelson is the 20th Logan recipient of this prestigious certification under Norman W. Kettner, DC, DACBR, FICC, professor and chair of the Department of Radiology, and radiology department faculty. 


Dr. Norman Kettner: Combining Radiology with Chiropractic Medicine

June 10, 2019 -- Norman Kettner, DC, DACBR, FICC, professor and chair of the Department of Radiology, was recently featured in AXIS Imaging News as one of the most influential professionals in radiology.

Check out the full article here – where Dr. Kettner answers five questions about his career, research, his unique approach that combines radiology with chiropractic care, and what he believes the future of diagnostic imaging will hold.

Logan Adjunct Faculty Member Receives Prestigious Award

June 7, 2019 -- The Academy for Radiology & Biomedical Imaging Research has recognized Logan radiology adjunct faculty member Vitaly Napadow PhD, LicAc. with the Academy’s 2019 Distinguished Investigator Award.

Dr. Napadow is one of 37 researchers to receive the award, which recognizes individuals for their accomplishments in the field of medical imaging. Recipients represent the top 10 percent of all academic radiology faculty.

Dr. Napadow serves as director for the Center for Integrative Pain Neuroimaging (CiPNI) and associate professor for the Martinos Center for Biomedical Imaging at Massachusetts General Hospital, the primary teaching hospital for Harvard Medical School.

 

In addition to serving as an adjunct faculty member at Logan, Dr. Napadow has been a research collaborator with Norman Kettner, DC, DACBR, FICC, chair of Logan’s Department of Radiology, for nearly 20 years.

 

According to Elizabeth A. Krupinski, PhD, co-chair of the Council of Distinguished Investigators, the award recipients represent the future of research in radiology, advancing the field and developing ways to significantly improve patient care through imaging.

 

Each of the honorees has met the following criteria:

  • Primary professional appointment in an academic Department of Radiology;
  • Recipient of a MD, DO, and/or PhD degree;
  • Academic rank of at least Associate Professor or its equivalent;
  • Significant research contributions;
  • Sustained productivity, including at least 25 peer-reviewed scientific research publications in which the awardee is the first author or senior author; and
  • Demonstrated accomplishments as an independent investigator with a substantial ongoing research program, including at least 6 cumulative years of funding as the Principal Investigator of a major competitive extramural research grant.

Honorees will be inducted into the Academy’s Council of Distinguished Investigators during a ceremony that will be held in November at the Radiological Society of North America’s 2019 annual meeting in Chicago.


Neuromodulation Journal Publishes Logan Research

March 21, 2019 -- Brain Stimulation, a premier journal for original research in the field of neuromodulation, has published research co-authored by Norman W. Kettner, DC, DACBR, DCBCN, FICC, chair of Logan’s Department of Radiology.

The study looked at the vagus nerve, which originates in the brain stem and is responsible for a variety of systems operations in the body, including the cardiovascular, immune and metabolic. Specifically, Dr. Kettner’s research wanted to determine if targeting vagal nuclei in response to stimulation was enhanced when the stimulation was delivered during exhalation.

To find out, researchers used a multimodal ultrahigh-field (7T) fMRI to examine vagal nuclei in the brain stem while applying a respiratory-gaited auricular vagal afferent nerve stimulation (RAVENS) technique. The transcutaneous electrical stimulation was applied in the ear at the cymba conchae. The results demonstrated that targeting was indeed enhanced during exhalation. This work will translate to nonpharmacological approaches for modulating brain activity in chronic pain and other neurological conditions.

Dr. Kettner’s co-researchers included Roberta Sclocco, PhD, and Vitaly Napadow, PhD, who are affiliated with Logan University, Department of Radiology through the Athinoula A. Martinos Center for Biomedical Imaging at Massachusetts General Hospital.

Dr. Kettner said he was honored to have research accepted by Brain Stimulation. “The journal focuses on research that promises to noninvasively modulate the nervous system and function of the brain,” he said. “Our research achieved that, and offers a brand new field of study.”


 


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