August 16, 2019 -- A recent case
study authored by members of the department of radiology and a Health Center clinician
was published in Journal of Ultrasound. It reported that an 8-year-old
patient with Duchenne muscular dystrophy (DMD) displayed increased sonoelastographic
measures (hardening) of lower extremity muscles when compared with an
age-matched healthy control. The report also demonstrated the value of using
sonoelastography, a noninvasive ultrasound technique, to diagnose and monitor
the progress of DMD.
case study, titled “Sonoelastography of the trunk and lower extremity muscles
in a case of Duchenne muscular dystrophy,” was written by Stacey Cornelson, DC,
DACBR; Ashley Ruff, DC; Muriel Perillat, DC, MS,; and Norman Kettner, DC,
DACBR, FICC, professor and chair of the Department of Radiology.
is a rare genetic disorder that causes muscle weakness and reduced tone of the
core and lower extremities through replacement of muscle by fibrofatty tissue.
Sonoelastography ultrasound can be used to demonstrate changes in the muscle
mechanical properties due to fatty replacement and fibrosis. Thus far, the use
of ultrasound technology in diagnosing DMD patients has been limited. Muscle
biopsy is the standard for histologic diagnosis of DMD, but ultrasound may be a
noninvasive and more cost-effective approach to assess muscle changes and
response to treatment. A goal of this case report was to add to the growing
argument for this approach.
case study also demonstrated the value of chiropractic care for treating DMD
symptoms. The patient came to Dr. Perillat for palliative care of low back and
bilateral leg pain and headaches. Among other symptoms, a physical exam
revealed a mild waddling gait, bilateral pseudohypertrophy of the calf muscles
and abnormal spinal ranges of motion. The patient also required assistance to
climb a flight of stairs.
addition to sonoelastographic ultrasound to assess muscle stiffness and texture,
the patient underwent spinal mobilization, kinesiotaping of lower extremity
muscles and was also fitted for foot orthotics to ease the abnormal gait. The
patient reported pain reduction and some improvement in gait and required less
assistance to climb stairs.
9, 2019 -- Kenneth Weber II, DC, PhD, an instructor in the
Department of Anesthesiology, Perioperative and Pain Medicine at Stanford
University, recently spoke as part of the Logan Department of Radiology’s
Chiropractic Grand Rounds.
Dr. Weber, who earned his clinical training as a
chiropractor at Palmer College of Chiropractic Florida and then completed a PhD
in neuroscience at Northwestern University, currently researches different
neuroscience, machine-learning and clinical research techniques to better
understand, treat, and prevent musculoskeletal and neurological conditions,
including spinal pain.
On August 2, he addressed the topic of advancing
chiropractic with advanced magnetic resonance imaging to students, faculty and
staff, opening with a general description of the structural
and functional magnetic resonance imaging (fMRI) technology along
with their advantages and disadvantages. He described how fMRI provides non-invasive
mapping of the brain’s neuroanatomy and neurophysiology in the assessment of
patients with chronic pain. Maladaptive neural
circuity develops as an adaptive response to the persistent
nociception. This adaptation to central sensitization utilizes cortical
and subcortical neuroplasticity, and these patterns of brain neural activity
are mapped with fMRI technology. Dr. Weber discussed his research in
brain-based models of clinical pain states, and has incorporated an artificial
intelligence method known as machine learning to enhance models of bran
responses to pain.
He also explained his extensive research of spinal
manipulation in healthy and clinical pain disorders, including a new
development in his research: spinal cord fMRI. This technique, which Dr.
Kettner said has been long hampered by technical challenges, is advancing and
may provide a biomarker of spinal cord injury and disorders. In addition,
simultaneous fMRI of the spinal cord combined with functional imaging
of the brain is now on the horizon.
Dr. Kettner said this corticospinal mapping will provide
a perspective of large neural network integration, allowing more
precise understanding of chronic pain and other associated disorders, such as
anxiety and depression, and their treatment outcomes.
29, 2019 -- Please join us in congratulating Stacey Cornelson, DC who
recently earned the Diplomate (DACBR) status by the American Chiropractic
Board of Radiology.
Dr. Cornelson is the 20th Logan
recipient of this prestigious certification under Norman W. Kettner,
DC, DACBR, FICC, professor and chair of the Department of Radiology, and radiology department faculty.
2019 -- Norman
Kettner, DC, DACBR, FICC, professor and chair of the Department of
Radiology, was recently featured in AXIS
Imaging News as one of the most influential professionals in radiology.
Check out the full article here – where
Dr. Kettner answers five questions about his career, research, his unique
approach that combines radiology with chiropractic care, and what he believes
the future of diagnostic imaging will hold.
June 7, 2019 -- The Academy for
Radiology & Biomedical Imaging Research has recognized Logan
radiology adjunct faculty member Vitaly Napadow PhD, LicAc. with
the Academy’s 2019 Distinguished Investigator Award.
Napadow is one of 37 researchers to receive the award, which recognizes
individuals for their accomplishments in the field of medical imaging. Recipients
represent the top 10 percent of all academic radiology faculty.
Dr. Napadow serves as director for
the Center for Integrative Pain Neuroimaging (CiPNI) and associate professor
for the Martinos Center for Biomedical Imaging at Massachusetts General
Hospital, the primary teaching hospital for Harvard Medical School.
In addition to serving as an adjunct
faculty member at Logan, Dr. Napadow has been a research collaborator with Norman
Kettner, DC, DACBR, FICC,
chair of Logan’s Department of Radiology, for nearly 20 years.
According to Elizabeth A. Krupinski,
PhD, co-chair of the Council of Distinguished Investigators, the award
recipients represent the future of research in radiology, advancing the field
and developing ways to significantly improve patient care through imaging.
of the honorees has met the following criteria:
- Primary professional
appointment in an academic Department of Radiology;
- Recipient of a MD,
DO, and/or PhD degree;
- Academic rank of at
least Associate Professor or its equivalent;
productivity, including at least 25 peer-reviewed scientific research
publications in which the awardee is the first author or senior author; and
accomplishments as an independent investigator with a substantial ongoing
research program, including at least 6 cumulative years of funding as the
Principal Investigator of a major competitive extramural research grant.
Honorees will be inducted into the Academy’s Council
of Distinguished Investigators during a ceremony that will be held in
November at the Radiological Society of North America’s 2019 annual meeting in
March 21, 2019 -- Brain
Stimulation, a premier journal for original research in the field of
neuromodulation, has published research co-authored by Norman W. Kettner,
DC, DACBR, DCBCN, FICC, chair of Logan’s Department of Radiology.
The study looked at the vagus nerve,
which originates in the brain stem and is responsible for a variety of systems
operations in the body, including the cardiovascular, immune and metabolic.
Specifically, Dr. Kettner’s research wanted to determine if targeting vagal
nuclei in response to stimulation was enhanced when the stimulation was
delivered during exhalation.
To find out, researchers used a
multimodal ultrahigh-field (7T) fMRI to examine vagal nuclei in the brain stem
while applying a respiratory-gaited auricular vagal afferent nerve stimulation
(RAVENS) technique. The transcutaneous electrical stimulation was applied in
the ear at the cymba conchae. The results demonstrated that targeting was
indeed enhanced during exhalation. This work will translate to
nonpharmacological approaches for modulating brain activity in chronic pain and
other neurological conditions.
Dr. Kettner’s co-researchers
included Roberta Sclocco, PhD, and Vitaly Napadow, PhD, who are affiliated with
Logan University, Department of Radiology through the Athinoula A. Martinos
Center for Biomedical Imaging at Massachusetts General Hospital.
Dr. Kettner said he was honored to
have research accepted by Brain
Stimulation. “The journal focuses on research that promises to
noninvasively modulate the nervous system and function of the brain,” he said.
“Our research achieved that, and offers a brand new field of study.”